Repolarizing heterogeneous leukemia-associated macrophages with more M1 characteristics eliminates their pro-leukemic effects

Macrophages exhibit phenotypic heterogeneity under both physiological and pathological conditions. Applications targeting M2-like tumor-associated macrophages (TAMs) improve outcome in solid tumors. Considerable differences are detected between leukemia-associated macrophages (LAMs) and TAMs. Howeve...

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主要な著者:	Xiao Yang, Wenli Feng, Rong Wang, Feifei Yang, Lina Wang, Shayan Chen, Yongxin Ru, Tao Cheng, Guoguang Zheng
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis Group 2018-04-01
シリーズ:	OncoImmunology
主題:	irf7 leukemia-associated macrophages phenotypic heterogeneity phenotype conversion sapk/jnk pathway
オンライン･アクセス:	http://dx.doi.org/10.1080/2162402X.2017.1412910
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