Single-cell transcriptomic analysis reveals a decrease in the frequency of macrophage-RGS1high subsets in patients with osteoarticular tuberculosis

Abstract Background Cell subsets differentially modulate host immune responses to Mycobacterium tuberculosis (MTB) infection. However, the nature and functions of these subsets against osteoarticular tuberculosis (OTB) are unclear. Here, we aimed to understand the phenotypes and functions of immune...

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Hlavní autoři:	Ying Jiang, Xinqiang Zhang, Bo Wang, Liping Tang, Xin Liu, Xiudong Ding, Yueming Dong, Hong Lei, Di Wang, Huicheng Feng
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-08-01
Edice:	Molecular Medicine
Témata:	Osteoarticular tuberculosis scRNA Biomarker Macrophages Ferroptosis
On-line přístup:	https://doi.org/10.1186/s10020-024-00886-9
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