Design and Characterization of a Novel eEF2K Degrader with Potent Therapeutic Efficacy Against Triple‐Negative Breast Cancer

Abstract Dysregulated eEF2K expression is implicated in the pathogenesis of many human cancers, including triple‐negative breast cancer (TNBC), making it a plausible therapeutic target. However, specific eEF2K inhibitors with potent anti‐cancer activity have not been available so far. Targeted prote...

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Váldodahkkit:	Changxin Zhong, Rongfeng Zhu, Ting Jiang, Sheng Tian, Xiaobao Zhao, Xiaoya Wan, Shilong Jiang, Zonglin Chen, Rong Gong, Linhao He, Jin‐Ming Yang, Na Ye, Yan Cheng
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Wiley 2024-02-01
Ráidu:	Advanced Science
Fáttát:	degrader eEF2K molecular glue triple‐negative breast cancer
Liŋkkat:	https://doi.org/10.1002/advs.202305035
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