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First molecular insight into Ovar-DRB1 exon 2 in Edilbay sheep: High heterozygosity and detection of novel variants

Background and Aim: The Ovar-DRB1 gene, a key component of the sheep main histocompatibility complex (MHC) class II region, plays a critical role in antigen presentation and immune responsiveness. Despite the well-documented hypervariability of exon 2 in many sheep breeds, no study has yet examined...

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Principais autores: Saida N. Marzanova, Davud A. Devrishov, Vladislav A. Zuchkov, Nurbiy S. Marzanov, Elizaveta A. Nikolaeva
Formato: Artigo
Idioma:Inglês
Publicado: Veterinary World 2025-12-01
Series:Veterinary World
Assuntos:
edilbay sheep
genetic diversity
immunogenetics
kazakh sheep breed
major histocompatibility complex
novel alleles
ovar-drb1 exon 2
polymorphism
sanger sequencing
sheep immune genetics
Acceso en liña:https://veterinaryworld.org/Vol.18/December-2025/21.pdf
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