The Multifaceted Role of Pyroptosis: Molecular Mechanisms, Crosstalk with Other Cell Death Pathways, and Therapeutic Implications

ABSTRACT Pyroptosis is a tightly regulated, proinflammatory form of programmed cell death defined by gasdermin‐mediated membrane pore formation and cytokine release. By coupling cell death to innate immune activation, pyroptosis occupies a unique position at the interface of host defense and tissue...

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Autors principals:	Diego Liviu Boaru, Patricia De Castro‐Martinez, Cielo Garcia‐Montero, Oscar Fraile‐Martinez, Majd N. Michael Alhaddadin, Silvestra Barrena‐Blázquez, Laura Lopez‐Gonzalez, Clara Tasende Fernández, Ricardo Alvarado‐Hurtado, Tomás Ratia Giménez, Inmaculada Lasa‐Unzúe, Manuel Díez Alonso, Alberto Gutiérrez‐Calvo, Miguel A. Saez, David Cobo‐Prieto, Jose V. Saz, Melchor Alvarez‐Mon, Raul Diaz‐Pedrero, Miguel A. Ortega
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2026-07-01
Col·lecció:	MedComm
Matèries:	apoptosis cancer extracellular vesicles nanoparticles PANoptosis pyroptosis
Accés en línia:	https://doi.org/10.1002/mco2.70844
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