Molecular Mechanism of Targeted Inhibition of Pancreatic Lipase and Cholesterol Esterase by Hempseed Peptides

In this study, we systematically investigated the regulatory effects of two hempseed peptides (APAM and RLPA) on pancreatic lipase (PL) and cholesterol esterase (CE) activities and the molecular binding mechanism using enzyme kinetics, synergistic inhibition, fluorescence spectroscopy, isothermal ti...

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Hlavní autor:	YIN Hao, ZHU Jiangxiong, ZHAO Haiyun, ZHONG Yu, WANG Danfeng, DENG Yun
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	China Food Publishing Company 2025-01-01
Edice:	Shipin Kexue
Témata:	lipid-digesting enzymes; inhibition mechanism; fluorescence spectroscopy; isothermal titration calorimetry; molecular modeling
On-line přístup:	https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-2-005.pdf
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