Liberation of host heme by Clostridioides difficile-mediated damage enhances Enterococcus faecalis fitness during infection

ABSTRACTToxin production by Clostridioides difficile damages the colonic epithelium and leads to a robust inflammatory response. This disruption of the epithelial barrier markedly alters the nutritional landscape in the C. difficile-infected gut. The impact of toxin-mediated nutritional remodeling d...

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Bibliografische Detailangaben

Hauptverfasser:	Alexander B. Smith, Jonathan T. Specker, Katharine K. Hewlett, Troy R. Scoggins, Montana Knight, Abigail M. Lustig, Yanhong Li, Kirsten M. Evans, Yingchan Guo, Qianxuan She, Michael W. Christopher, Timothy J. Garrett, Ahmed M. Moustafa, Daria Van Tyne, Boone M. Prentice, Joseph P. Zackular
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2024-01-01
Schriftenreihe:	mBio
Schlagworte:	Clostridioides difficile Enterococcus heme infectious disease gut microbiome microbial ecology
Online-Zugang:	https://journals.asm.org/doi/10.1128/mbio.01656-23
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