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Gastrointestinal Mechanisms Underlying the Cardiovascular Effect of Metformin

Metformin, the most widely prescribed drug therapy for type 2 diabetes, has pleiotropic benefits, in addition to its capacity to lower elevated blood glucose levels, including mitigation of cardiovascular risk. The mechanisms underlying the latter remain unclear. Mechanistic studies have, hitherto,...

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Principais autores: Malcolm J. Borg, Christopher K. Rayner, Karen L. Jones, Michael Horowitz, Cong Xie, Tongzhi Wu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-11-01
Serier:Pharmaceuticals
Fag:
metformin
cardiovascular
gastrointestinal
mechanisms
bile acids
gut microbiota
Online adgang:https://www.mdpi.com/1424-8247/13/11/410
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