When cytology misses and ultrasound warns: the predictive role of BRAFV600E mutation in thyroid nodules

PurposeThyroid nodules with high-suspicion ultrasound features but benign cytologic findings remain a diagnostic challenge due to potential false-negative fine-needle aspiration (FNA) results. The BRAFV600E mutation, a hallmark of papillary thyroid carcinoma (PTC), may improve malignancy risk strati...

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Auteurs principaux:	Liu Jie, Cai Wenqing, Zhang Guang, Li Shijie, Fu Qingfeng, Li Kangping, Yu Yuexin, Chen Zhuo, Carla Colombo, Francesco Brucchi, Gianlorenzo Dionigi, Liu Xiaoli
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2026-03-01
Collection:	Frontiers in Endocrinology
Sujets:	BRAFV600E mutation fine-needle aspiration molecular diagnostics papillary thyroid carcinoma thyroid nodules
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fendo.2026.1803314/full
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