Chemotherapy-related agranulocytosis as a predictive factor for germline BRCA1 pathogenic variants in breast cancer patients: a retrospective cohort study

BACKGROUND: Carriers of germline pathogenic variants of the BRCA1 gene (gBRCA1) tend to have a higher incidence of haematological toxicity upon exposure to chemotherapy. We hypothesised that the occurrence of agranulocytosis during the first cycle of (neo-)adjuvant chemotherapy (C1) in breast cance...

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Glavni autori:	Noémie Lang, Aurélie Ayme, Chang Ming, Jean‑Damien Combes, Victor N. Chappuis, Alex Friedlaender, Aurélie Vuilleumier, José L. Sandoval, Valeria Viassolo, Pierre O. Chappuis, S. Intidhar Labidi-Galy
Format:	Artigo
Jezik:	Inglês
Izdano:	SMW supporting association (Trägerverein Swiss Medical Weekly SMW) 2023-03-01
Serija:	Swiss Medical Weekly
Online pristup:	https://smw.ch/index.php/smw/article/view/3307
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