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Closing the system: production of viral antigen-presenting dendritic cells eliciting specific CD8+ T cell activation in fluorinated ethylene propylene cell culture bags

Abstract Background A major obstacle to anti-viral and -tumor cell vaccination and T cell immunotherapy is the ability to produce dendritic cells (DCs) in a suitable clinical setting. It is imperative to develop closed cell culture systems to accelerate the translation of promising DC-based cell the...

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Principais autores: Jean-Philippe Bastien, Natalie Fekete, Ariane V. Beland, Marie-Paule Lachambre, Veronique Laforte, David Juncker, Vibhuti Dave, Denis-Claude Roy, Corinne A. Hoesli
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-10-01
coleção:Journal of Translational Medicine
Assuntos:
Cellular therapy
Dendritic cell
Fluorinated polymers
Immunotherapy
Monocyte
Polystyrene
Acesso em linha:http://link.springer.com/article/10.1186/s12967-020-02543-1
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