Tissue-type Plasminogen Activator (tPA) Modulates the Postsynaptic Response of Cerebral Cortical Neurons to the Presynaptic Release of Glutamate

Tissue-type plasminogen activator (tPA) is a serine proteinase released by the presynaptic terminal of cerebral cortical neurons following membrane depolarization (Echeverry et al., 2010). Recent studies indicate that the release of tPA triggers the synaptic vesicle cycle and promotes the exocytosis...

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Autores principales:	Valerie Jeanneret, Fang Wu, Paola Merino, Enrique Torre, Ariel Diaz, Lihong Cheng, Manuel Yepes
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2016-11-01
Colección:	Frontiers in Molecular Neuroscience
Materias:	Plasminogen Protein Phosphatase 1 homeostatic plasticity Calcium calmodulin dependent kinase II (CaMKII) tissue-type plasminogen activator
Acceso en línea:	http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00121/full
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