iCLIP predicts the dual splicing effects of TIA-RNA interactions.
The regulation of alternative splicing involves interactions between RNA-binding proteins and pre-mRNA positions close to the splice sites. T-cell intracellular antigen 1 (TIA1) and TIA1-like 1 (TIAL1) locally enhance exon inclusion by recruiting U1 snRNP to 5' splice sites. However, effects of TIA...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Public Library of Science (PLoS)
2010-10-01
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| Schriftenreihe: | PLoS Biology |
| Online-Zugang: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1000530&type=printable |
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