Long noncoding RNA Smyca coactivates TGF-β/Smad and Myc pathways to drive tumor progression

Abstract Background Metastasis and chemoresistance are major culprits of cancer mortality, but factors contributing to these processes are incompletely understood. Methods Bioinformatics methods were used to identify the relations of Smyca expression to clinicopathological features of human cancers....

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Κύριοι συγγραφείς:	Hsin-Yi Chen, Shu-Jou Chan, Xinxin Liu, An-Chi Wei, Ru-In Jian, Kuan-Wei Huang, Yaw-Dong Lang, Jou-Ho Shih, Chun-Chieh Liao, Chiu-Lin Luan, Yu-Tung Kao, Shang-Yin Chiang, Pei-Wen Hsiao, Yuh-Shan Jou, Yunching Chen, Ruey-Hwa Chen
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2022-07-01
Σειρά:	Journal of Hematology & Oncology
Θέματα:	LncRNA TGF-β Smad c-Myc EMT Metastasis
Διαθέσιμο Online:	https://doi.org/10.1186/s13045-022-01306-3
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