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Substrate stiffness and pressure alter retinal Müller glia response and extracellular matrix production

Background: The retina is highly influenced by its mechanical environment, with Müller glia (MG) acting as key mechanosensors and extracellular matrix (ECM) producers. This study examined MG responses to substrate stiffness and high pressure (HP), and whether TGF-β1 modulation could mitigate these e...

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Autores principales: Laura Prieto-López, Xandra Pereiro, Emilio J. González Ramírez, Noelia Ruzafa, Alicia Alonso, Kristian Franze, Elena Vecino
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2025-09-01
Colección:Biomaterials and Biosystems
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Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2666534425000091
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