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Engineering rules that minimize germline silencing of transgenes in simple extrachromosomal arrays in C. elegans

C. elegans has strong repressive mechanisms that silence transgenes in the germline. Here the authors elucidate the design rules for efficient germline expression.

Furkejuvvon:
Bibliográfalaš dieđut
Váldodahkkit: Mohammed D. Aljohani, Sonia El Mouridi, Monika Priyadarshini, Amhed M. Vargas-Velazquez, Christian Frøkjær-Jensen
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2020-12-01
Ráidu:Nature Communications
Liŋkkat:https://doi.org/10.1038/s41467-020-19898-0
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