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Characterization of PSOP26 as an ookinete surface antigen with improved transmission-blocking activity when fused with PSOP25

Abstract Background The Plasmodium zygote-to-ookinete developmental transition is an essential step for establishing an infection in the mosquito vector, and antigens expressed during this stage are potential targets for transmission-blocking vaccines (TBVs). The secreted ookinete protein 26 (PSOP26...

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Principais autores: Peng-peng Wang, Xuefeng Jiang, Jie Bai, Fan Yang, Xinxin Yu, Yudi Wu, Wenqi Zheng, Yongzhe Zhang, Liwang Cui, Fei Liu, Xiaotong Zhu, Yaming Cao
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-05-01
Serier:Parasites & Vectors
Fag:
Plasmodium berghei
Gamete
Ookinete
Fertilization
Transmission-blocking
Online adgang:https://doi.org/10.1186/s13071-022-05294-8
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