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Alkaloidal Fraction Reduces Paracellular Permeability, IL-8 and NS1 Production on Human Microvascular Endothelial Cells Infected with Dengue Virus

Dengue is the major Arbovirus in the world, annually causing morbidity and death. Severe dengue is associated with changes in the endothelial barrier function due to the production of inflammatory mediators by immune cells and by the endothelium. Dengue virus (DENV) replicates efficiently in human e...

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Autores principales: Raimundo Sousa Lima-Junior, Cintia da Silva Mello, Antonio Carlos Siani, Ligia M. Marino Valente, Claire Fernandes Kubelka
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publishing 2013-11-01
Colección:Natural Product Communications
Acceso en línea:https://doi.org/10.1177/1934578X1300801112
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