Interleukin-11 disrupts alveolar epithelial progenitor function

Background Interleukin-11 (IL-11) is linked to the pathogenesis of idiopathic pulmonary fibrosis (IPF), since IL-11 induces myofibroblast differentiation and stimulates their excessive collagen deposition in the lung. In IPF there is disrupted alveolar structural architecture, yet the effect of IL-1...

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Autores principales:	Rosa K. Kortekaas, Kerstin E. Geillinger-Kästle, Theo Borghuis, Kaoutar Belharch, Megan Webster, Wim Timens, Janette K. Burgess, Reinoud Gosens
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	European Respiratory Society 2023-05-01
Colección:	ERJ Open Research
Acceso en línea:	http://openres.ersjournals.com/content/9/3/00679-2022.full
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