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A GABAergic neural circuit from the suprachiasmatic nucleus to DG drives cognitive impairment in migraine mice

Abstract Background Cognitive impairment and circadian rhythm disturbances are prevalent comorbidities of migraine, yet their underlying neural circuit mechanisms remain poorly understood. The suprachiasmatic nucleus (SCN), as the master circadian pacemaker, and the hippocampus, essential for memory...

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Principais autores: Qingfang Xie, Yu Zhang, Ying Huang, Wen Yan, Yanjie Zhou, Zheman Xiao
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-03-01
coleção:The Journal of Headache and Pain
Assuntos:
Migraine
Cognitive impairment
Suprachiasmatic Nucleus
Hippocampus
GABA
Neural circuit
Acesso em linha:https://doi.org/10.1186/s10194-026-02341-y
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