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Generation and Characterization of Cisplatin-Resistant Oral Squamous Cell Carcinoma Cells Displaying an Epithelial–Mesenchymal Transition Signature

Cisplatin resistance remains a major therapeutic challenge in oral squamous cell carcinoma (OSCC), leading to treatment failure and poor outcomes. This study aimed to generate and characterize cisplatin-resistant OSCC models to elucidate resistance mechanisms. Two resistant OSCC cell lines (SCC-9R a...

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Kaydedildi:
Asıl Yazarlar: Everton Freitas de Morais, Lilianny Querino Rocha de Oliveira, Cintia Eliza Marques, Fábio Haach Téo, Gisele Vieira Rocha, Camila Oliveira Rodini, Clarissa A. Gurgel, Tuula Salo, Edgard Graner, Ricardo D. Coletta
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2025-08-01
Seri Bilgileri:Cells
Konular:
oral squamous cell carcinoma
cisplatin resistance
tumor plasticity
epithelial–mesenchymal transition
biomarkers
Online Erişim:https://www.mdpi.com/2073-4409/14/17/1311
Etiketler: Etiketle
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