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Transcription Factor KLF10 Constrains IL-17-Committed Vγ4+ γδ T Cells

γδ T cells, known to be an important source of innate IL-17 in mice, provide critical contributions to host immune responses. Development and function of γδ T cells are directed by networks of diverse transcription factors (TFs). Here, we examine the role of the zinc finger TFs, Kruppel-like factor...

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Principais autores: Girak Kim, Min Jeong Gu, Soo Ji Kim, Kwang Hyun Ko, Yoon-Chul Kye, Cheol Gyun Kim, Jae-Ho Cho, Woon-Kyu Lee, Ki-Duk Song, Hyuk Chu, Yeong-Min Park, Seung Hyun Han, Cheol-Heui Yun
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-02-01
Serier:Frontiers in Immunology
Fag:
KLF10
γδ T cells
IL-17
homeostasis
Innate-like γδ-17
Online adgang:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00196/full
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