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Effect of CXCR5, PD‐1 and ICOS on B‐cell responses and relevance to myasthenia gravis

Abstract Objectives T follicular helper (Tfh) cells regulate B‐cell responses within germinal centres primarily via programmed cell death protein 1 (PD‐1) and inducible T‐cell costimulator (ICOS), whereas CXC chemokine receptor type 5 (CXCR5)‐negative T peripheral helper (Tph) cells provide similar...

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Main Authors: Merve Çebi, Arman Çakar, Hacer Durmuş, Yeşim Parman, Güher Saruhan‐Direskeneli
Format: Artigo
Language:Inglês
Published: Wiley 2026-06-01
Series:Clinical & Translational Immunology
Subjects:
CXCR5
ICOS
myasthenia gravis
PD‐1
T follicular helper cells
T peripheral helper cells
Online Access:https://doi.org/10.1002/cti2.70112
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