Creation of a eukaryotic multiplexed site-specific inversion system and its application for metabolic engineering

Abstract The site-specific recombination system is a versatile tool in genome engineering, enabling controlled DNA inversion or deletion at specific sites to generate genetic diversity. The multiplexed inversion system, which preferentially facilitates inversion at reverse-oriented sites rather than...

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Autors principals:	Jieyi Li, Simiao Gong, Yuan Ma, Peiyan Han, Nan Wang, Zongheng Fu, Xinyi Zhang, Xinyang Huang, Tianyu Yang, Hanze Tong, Guang-Rong Zhao, Yi Wu, Ying-Jin Yuan
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-02-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-025-57206-w
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