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Transcriptomic profiling of single circulating tumor cells provides insight into human metastatic gastric cancer

Ryo Negishi et al. utilize a size-dependent recovery method with gel-based cell manipulation to isolate single circulating tumor cells (CTCs) for transcriptomic analysis. They demonstrate the utility of this approach by analyzing the transcriptomic profile of CTCs from human gastric cancer patients.

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Hoofdauteurs: Ryo Negishi, Hitomi Yamakawa, Takeru Kobayashi, Mayuko Horikawa, Tatsu Shimoyama, Fumiaki Koizumi, Takeshi Sawada, Keisuke Oboki, Yasushi Omuro, Chikako Funasaka, Akihiko Kageyama, Yusuke Kanemasa, Tsuyoshi Tanaka, Tadashi Matsunaga, Tomoko Yoshino
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2022-01-01
Reeks:Communications Biology
Online toegang:https://doi.org/10.1038/s42003-021-02937-x
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