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Epigenetic activation of VEGFA by SMARCD1 mediates tumor progression and bevacizumab resistance in clear cell renal cell carcinoma

Abstract Background Clear cell renal cell carcinoma (ccRCC) is an aggressive malignancy characterized by strong invasiveness and treatment resistance. Although SMARCD1 has been studied in several cancers, its function in ccRCC and its regulatory relationship with the key angiogenic factor VEGFA rema...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Hanqing Liu, Yan Shen, Yuchen Hou, Congyun Xu, Xiaoyu Bai, Yixun Liu, Jun Xiao
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2026-03-01
Rangatū:BMC Cancer
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12885-026-15791-z
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