Effect of time on reperfusion in acute ischemic stroke treated with thrombolysis within the 4.5-hour window: a secondary analysis of the AcT Trial

Background: It is unclear if revascularization therapies become less effective at recanalizing occlusions over time. We evaluated the association between time metrics and successful reperfusion in patients treated with thrombolysis for anterior circulation large vessel occlusion (LVO) strokes. Metho...

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Prif Awduron:	Katrina Hannah D. Ignacio, MD, MSc, Umberto Pensato, MD, Fouzi Bala, MD, MSc, Brian Buck, MD, Tolulope Sajobi, PhD, Luciana Catanese, MD, Aleksander Tkach, MD, Richard Swartz, MD, Andrew Demchuk, MD, Mohammed A. Almekhlafi, MD, MSc, Bijoy K. Menon, MD, MSc, Aravind Ganesh, MD, DPhil, Nishita Singh, MD, MSc
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2026-07-01
Cyfres:	Journal of Stroke and Cerebrovascular Diseases
Pynciau:	Acute ischemic stroke Reperfusion outcomes Door-to-needle time Door-to-groin time Tenecteplase Alteplase
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S1052305726001308
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