Long-Term Culturing of FreeStyle 293-F Cells Affects Immunoglobulin G Glycome Composition

Glycosylation of IgG regulates the effector function of this antibody in the immune response. Glycosylated IgG is a potent therapeutic used for both research and clinical purposes. While there is ample research on how different cell culture conditions affect IgG glycosylation, the data are missing o...

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Bibliografische Detailangaben

Hauptverfasser:	Fran Lukšić, Anika Mijakovac, Goran Josipović, Vedrana Vičić Bočkor, Jasminka Krištić, Ana Cindrić, Martina Vinicki, Filip Rokić, Oliver Vugrek, Gordan Lauc, Vlatka Zoldoš
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-08-01
Schriftenreihe:	Biomolecules
Schlagworte:	IgG glycosylation long-term cell culturing FreeStyle 293-F IgG glycoengineering cell aging
Online-Zugang:	https://www.mdpi.com/2218-273X/13/8/1245
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