Influence of traditional Chinese medicines on the in vivo metabolism of lopinavir/ritonavir based on UHPLC-MS/MS analysis

A fast, reliable, and cost-effective liquid chromatography-tandem mass spectrometry method was established to determine the effects of the traditional Chinese medicine employed to treat coronavirus disease 2019, namely, Lianhua Qingwen granules, Huoxiang Zhengqi capsules, Jinhua Qinggan granules, Sh...

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Autors principals:	Linlin Li, Xinxiang Yu, Dongmin Xie, Ningning Peng, Weilin Wang, Decai Wang, Binglong Li
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2022-04-01
Col·lecció:	Journal of Pharmaceutical Analysis
Matèries:	Lopinavir/ritonavir Combination of Chinese and western medicine Drug-drug interaction Ultra high-performance liquid chromatography-tandem mass spectrometry Pharmacokinetics COVID-19
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2095177921000666
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