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TGF-β1 Promotes Zika Virus Infection in Immortalized Human First-Trimester Trophoblasts via the Smad Pathway

The Zika virus (ZIKV) is well known for causing congenital Zika syndrome if the infection occurs during pregnancy; however, the mechanism by which the virus infects and crosses the placenta barrier has not been completely understood. In pregnancy, TGF-β1 is abundant at the maternal–fetal interface....

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Principais autores: Quang Duy Trinh, Ngan Thi Kim Pham, Kazuhide Takada, Chika Takano, Shihoko Komine-Aizawa, Satoshi Hayakawa
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-09-01
Serier:Cells
Fag:
Zika
trophoblasts
pregnancy
infection
congenital Zika syndrome
first trimester
Online adgang:https://www.mdpi.com/2073-4409/11/19/3026
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