Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid

Pharmacological interventions targeting mitochondria present several barriers for a complete efficacy. Therefore, a new mitochondriotropic antioxidant (AntiOxBEN3) based on the dietary antioxidant gallic acid was developed. AntiOxBEN3 accumulated several thousand-fold inside isolated rat liver mitoc...

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Bibliografische Detailangaben

Hauptverfasser:	José Teixeira, Catarina Oliveira, Fernando Cagide, Ricardo Amorim, Jorge Garrido, Fernanda Borges, Paulo J. Oliveira
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2018-01-01
Schriftenreihe:	Journal of Enzyme Inhibition and Medicinal Chemistry
Schlagworte:	Gallic acid mitochondriotropic antioxidant oxidative stress mitochondrial dysfunction mitochondrial permeability transition pore
Online-Zugang:	http://dx.doi.org/10.1080/14756366.2018.1442831
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