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YAP/TAZ activation mediates PQ-induced lung fibrosis by sustaining senescent pulmonary epithelial cells

Abstract Paraquat (PQ) is a widely used herbicide and a common cause of poisoning that leads to pulmonary fibrosis with a high mortality rate. However, the underlying mechanisms of PQ-induced pulmonary fibrosis and whether pulmonary epithelial cell senescence is involved in the process remain elusiv...

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Autors principals: Youjia Yu, Chunyan Chu, Kang Wang, Yan Li, Zhengsheng Mao, Li Hu, Jie Wang, Yanfang Yu, Hao Sun, Feng Chen
Format: Artigo
Idioma:Inglês
Publicat: BMC 2024-05-01
Col·lecció:Respiratory Research
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Accés en línia:https://doi.org/10.1186/s12931-024-02832-z
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