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Curcumin reverses cognitive deficits through promoting neurogenesis and synapse plasticity via the upregulation of PSD95 and BDNF in mice

Abstract Following prolonged exposure to hypoxic conditions, for example, due to ascent to high altitude, aging or stroke, cognitive deficits can develop. The exact nature and genesis of hypoxia-induced cognitive deficits remain unresolved. Curcumin has been reported to stimulate neurogenesis and re...

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Principais autores: Gaifen Li, Qiong Wu, Chao Wang, Pin Deng, Jiaxin Li, Zhiguang Zhai, Yubo Li
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-01-01
Serier:Scientific Reports
Fag:
Curcumin
Hypoxia
Neurogenesis
Synapse plasticity
Cognitive deficits
Online adgang:https://doi.org/10.1038/s41598-024-82571-9
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