The essential clathrin adapter protein complex-2 is tumor suppressive specifically in vivo
Abstract The microenvironment is a rich source of new cancer targets. We thus used a targeted single-guide RNA library to screen a panel of human pancreatic cancer lines for genes uniquely affecting tumorigenesis. Here we show inactivation of the Adapter Protein complex-2 of clathrin-mediated endocy...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Portfolio
2025-03-01
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| Collection: | Nature Communications |
| Accès en ligne: | https://doi.org/10.1038/s41467-025-57521-2 |
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