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Thalidomide Attenuates Mast Cell Activation by Upregulating SHP-1 Signaling and Interfering with the Action of CRBN

Allergy is a chronic inflammatory disease, and its incidence has increased worldwide in recent years. Thalidomide, which was initially used as an anti-emetic drug but was withdrawn due to its teratogenic effects, is now used to treat blood cancers. Although the anti-inflammatory and immunomodulatory...

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Bibliografiske detaljer
Principais autores: Hyeun-Wook Chang, Kyeong-Hwa Sim, Youn-Ju Lee
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-02-01
Serier:Cells
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Online adgang:https://www.mdpi.com/2073-4409/12/3/469
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