Polyubiquitin chain assembly and organisation determine the dynamics of protein activation and degradation
Protein degradation via ubiquitination is a major proteolytic mechanism in cells. Once a protein is destined for degradation, it is tagged by multiple ubiquitin molecules. The synthesised polyubiquitin chains can be recognised by the 26S proteosome where proteins are degraded. These chains form thro...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Frontiers Media S.A.
2014-01-01
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| Σειρά: | Frontiers in Physiology |
| Θέματα: | |
| Διαθέσιμο Online: | http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00004/full |
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