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Immunological mechanisms and antibody-drug conjugates targeting B7-H3 and B7-H4 in ovarian cancer

Ovarian cancer remains the most lethal gynecologic malignancy, with immune evasion a major driver of therapeutic resistance and disease progression. Among novel targets, the immune checkpoint molecules B7-H3 and B7-H4 have been recognized for their potent immunosuppressive roles and selective overex...

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Bibliografische gegevens
Hoofdauteurs: Emily Frances Brown, Ilaria Colombo, Ainhoa Madariaga, Lawrence Kasherman
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2025-11-01
Reeks:Frontiers in Immunology
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Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1683674/full
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