One-Step Affinity Purification of Leucine-Rich α₂-Glycoproteins from Snake Sera and Characterization of Their Phospholipase A₂-Inhibitory Activities as β-Type Phospholipase A₂ Inhibitors

Snakes contain three types of phospholipase A₂ (PLA₂)-inhibitory proteins in their blood, PLIα, β, and γ, which protect them from their own venom, PLA₂. PLIβ is the snake ortholog of leucine-rich α₂ glycoprotein (LRG). Since autologous cytochrome <i>c</i>...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Ryoichi Shirai, Kana Shibata, Shinobu Fujii, Rikiro Fukunaga, Seiji Inoue
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2024-03-01
Schriftenreihe:	Toxins
Schlagworte:	phospholipase A<sub>2</sub> inhibitor phospholipase A<sub>2</sub> leucine-rich α<sub>2</sub>-glycoprotein cytochrome <i>c</i> Viperidae Elapidae
Online-Zugang:	https://www.mdpi.com/2072-6651/16/3/126
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