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EXOSC4 as a novel regulator of neddylation in acute myeloid leukemia

Abstract Acute myeloid leukaemia (AML) is a common haematological malignancy with an unsatisfactory prognosis despite recent therapeutic advances. Neddylation and ferroptosis have been implicated in the regulation of malignant cell proliferation, survival and therapy response. However, the relations...

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Detalles Bibliográficos
Principais autores: Hai Guo, AoShuang Huang, Li Wang, Zihao Zhao, Ying Chen, Shaofei Xu, Shan Liu, JiShi Wang
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2026-05-01
Series:Scientific Reports
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Acceso en liña:https://doi.org/10.1038/s41598-026-52987-6
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