More than Meets the Eye: The Aryl Hydrocarbon Receptor is an Environmental Sensor, Physiological Regulator and a Therapeutic Target in Ocular Disease

The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor originally identified as an environmental sensor of xenobiotic chemicals. However, studies have revealed that the AHR regulates crucial aspects of cell growth and metabolism, development and the immune system. The importa...

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Principais autores:	Christine L. Hammond, Elisa Roztocil, Vardaan Gupta, Steven E. Feldon, Collynn F. Woeller
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-03-01
coleção:	Frontiers in Toxicology
Assuntos:	AHR (aryl hydrocarbon agonist) eye retina thyroid eye disease (TED) FICZ 6-formylindolo (3, 2-b) carbazole
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/ftox.2022.791082/full
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