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OPN promotes pro-inflammatory cytokine expression via ERK/JNK pathway and M1 macrophage polarization in Rosacea

Rosacea is a chronic inflammatory dermatosis that involves dysregulation of innate and adaptive immune systems. Osteopontin (OPN) is a phosphorylated glycoprotein produced by a broad range of immune cells such as macrophages, keratinocytes, and T cells. However, the role of OPN in rosacea remains to...

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Principais autores: Siyi Tang, Hao Hu, Manhui Li, Kaoyuan Zhang, Qi Wu, Xiaojuan Liu, Lin Wu, Bo Yu, Xiaofan Chen
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2024-01-01
叢編:Frontiers in Immunology
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1285951/full
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