The roles of Cryptochrome-1: the circadian clock as a control point in cancer therapy

Abstract In this review, we carefully describe the composition and operation of cryptochrome-1 (CRY1). We introduce four related signaling pathways, namely cAMP/PKA/CREB signaling way, HIFα signaling way, NF-κB signaling way, STAT3 signaling way, FOXO signaling pathway and Hedgehog (HH) signaling pa...

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Detalhes bibliográficos

Principais autores:	Yijia Liu, Yanzhe Huang, Hongliang Luo, Xueqin Lin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-06-01
coleção:	Journal of Translational Medicine
Assuntos:	CRY1 Circadian clock Cancer Signaling pathway In Silico
Acesso em linha:	https://doi.org/10.1186/s12967-025-06702-0
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