Diacylglycerol Kinase ζ Limits Cytokine-dependent Expansion of CD8+ T Cells with Broad Antitumor Capacity

Interleukin-2 and -15 drive expansion/differentiation of cytotoxic CD8+ T cells that eliminate targets via antigen-independent killing. This property is clinically relevant for the improvement of T cell-based antitumor therapies. Diacylglycerol kinase α and ζ (DGKα/ζ) metabolize the diacylglycerol g...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	Elena Andrada, Rosa Liébana, Isabel Merida
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2017-05-01
Saila:	EBioMedicine
Gaiak:	Immunotherapy Cancer Adoptive cell transfer Interleukin-2 Interleukin-15 CD8+ T lymphocytes Diacylglycerol kinase Lymphoma Anergy
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S2352396417301676
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!