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Molecular identification of sulfadoxine-pyrimethamine resistance in malaria infected women who received intermittent preventive treatment in the Democratic Republic of Congo

Abstract Background Point mutations in Plasmodium falciparum dihydrofolate reductase (Pfdhfr) and dihydropteroate synthase (Pfdhps) genes which confer resistance to sulfadoxine-pyrimethamine (SP) occur at increasing rates. The present study aimed to identify Pfdhfr and Pfdhps mutations in P. falcipa...

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Principais autores: Emrah Ruh, Jean Paul Bateko, Turgut Imir, Aysegul Taylan-Ozkan
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-01-01
coleção:Malaria Journal
Assuntos:
Plasmodium falciparum
Sulfadoxine-pyrimethamine
Drug resistance
Pfdhfr
Pfdhps
Democratic Republic of Congo
Acesso em linha:http://link.springer.com/article/10.1186/s12936-017-2160-x
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