Emerging roles of pyruvate dehydrogenase phosphatase 1: a key player in metabolic health

Pyruvate dehydrogenase phosphatase (PDP), a structurally conserved member of the protein phosphatase C family (PP2C) of proteins, is a key regulatory enzyme responsible for reactivation of the mitochondrial gate-keeper, pyruvate dehydrogenase (PDH). Tissue-specific expression of PDP isozymes, specif...

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Principais autores:	Vikalp Kumar, Miriam L. Greenberg
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-05-01
coleção:	Frontiers in Physiology
Assuntos:	pyruvate dehydrogenase complex pyruvate dehydrogenase phosphatase 1 cancer traumatic brain injury cardiomyogenesis barth syndrome
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphys.2025.1596636/full
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