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Rosiglitazone and a β3-Adrenoceptor Agonist Are Both Required for Functional Browning of White Adipocytes in Culture

The recruitment of brite (or beige) adipocytes has been advocated as a means to combat obesity, due to their ability to phenotypically resemble brown adipocytes (BA). Lineage studies indicate that brite adipocytes are formed by differentiation of precursor cells or by direct conversion of existing w...

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Principais autores: Jon Merlin, Masaaki Sato, Ling Yeong Chia, Richard Fahey, Mohsen Pakzad, Cameron J. Nowell, Roger J. Summers, Tore Bengtsson, Bronwyn A. Evans, Dana S. Hutchinson
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-05-01
Serier:Frontiers in Endocrinology
Fag:
adipocyte
beta adrenergic receptors
uncoupling protein 1
adrenoceptor
seahorse xf96 analysis
rosiglitazone
Online adgang:https://www.frontiersin.org/article/10.3389/fendo.2018.00249/full
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