Código QR (código de barras bidimensional)

Inhibitory Evaluation of Sulfonamide Chalcones on β-Secretase and Acylcholinesterase

The action of β-secretase (BACE1) is strongly correlated with the onset of Alzheimer’s disease (AD). Aminochalcone derivatives were examined for their ability to inhibit BACE1. Parent aminochalcones showed two digit micromolar IC50s against BACE1. Potency was enhanced 10-fold or m...

ver descrição completa

Na minha lista:
Principais autores: Dae Wook Kim, Heung Joo Yuk, Hye Jin Kim, Jin Hyo Kim, Hyung Won Ryu, Marcus J. Curtis-Long, Jung Keun Cho, Jae Eun Kang, Ki Hun Park
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2012-12-01
coleção:Molecules
Assuntos:
sulfonamide chalcone
Alzheimer&#8217
s disease (AD)
&#946
-secretase
acetylcholinesterase (AChE)
butyrylcholinesterase (BChE)
mixed inhibition
Acesso em linha:http://www.mdpi.com/1420-3049/18/1/140
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados