IL-39 promotes chronic graft-versus-host disease by increasing T and B Cell pathogenicity

Abstract Background Chronic graft-versus-host disease (cGVHD) remains a major complication during the late phase of allogeneic hematopoietic stem cell transplantation (allo-HSCT). IL-39, a newly described pro-inflammatory cytokine belonging to the IL-12 family, plays a role in lupus development. Rec...

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Autors principals:	Kangkang Lv, Bo Hu, Mingzhu Xu, Li Wan, Ziqi Jin, Mimi Xu, Yuanyuan Du, Kunpeng Ma, Quansheng Lv, Yang Xu, Lei Lei, Huanle Gong, Haiyan Liu, Depei Wu, Yuejun Liu
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-06-01
Col·lecció:	Experimental Hematology & Oncology
Matèries:	IL-39 IL-12 Chronic graft-versus-host disease Allogeneic hematopoietic stem cell transplantation
Accés en línia:	https://doi.org/10.1186/s40164-022-00286-x
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