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Spliceosomal Sm core assembly: AlphaFold 3 predicted structure and phosphorylation-dependent regulation of the human 6S complex

The in vivo assembly of uridine-rich small nuclear ribonucleoproteins (U snRNPs), the central catalytic components of the spliceosome, is a highly organised, multi-step process orchestrated by several multi-protein complexes. Structural analyses have provided valuable insights into their overall arc...

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Detalhes bibliográficos
Principais autores: Matthias Grimmler, Marco Reinhart, Sebastian Alers, Christoph Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science (AAAS) 2026-01-01
coleção:Computational and Structural Biotechnology Journal
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2001037025005471
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