Selective δ-Opioid Receptor Agonist, KNT-127, Facilitates Contextual Fear Extinction via Infralimbic Cortex and Amygdala in Mice

Facilitation of fear extinction is a desirable action for the drugs to treat fear-related diseases, such as posttraumatic stress disorder (PTSD). We previously reported that a selective agonist of the δ-opioid receptor (DOP), KNT-127, facilitates contextual fear extinction in mice. However, its site...

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Principais autores:	Ayako Kawaminami, Daisuke Yamada, Shoko Yanagisawa, Motoki Shirakata, Keita Iio, Hiroshi Nagase, Akiyoshi Saitoh
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-02-01
coleção:	Frontiers in Behavioral Neuroscience
Assuntos:	fear memory extinction δ-opioid receptor amygdala infralimbic cortex PTSD
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnbeh.2022.808232/full
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